Long-Term Use of Proton Pump Inhibitors Linked to Increased Risk of Stomach Cancer

Probably good to know for people who suffer from the associated problems the drugs are used for.

A class of drugs commonly used to treat acid reflux and heartburn has been linked to a greater-than-doubled risk of developing stomach cancer, a recent study has shown.

Proton pump inhibitors (PPIs) are used to suppress acid production in the stomach and are among the most widely sold drugs in the world, but a new study reveals that long-term use of the medicine can increase stomach cancer risks by almost 250 percent.

The risks are associated with a bacterium called Helicobacter pylori, carried by more than half of the world’s population – most often harmlessly, but in a small percentage of people, the bug has been tied to the development of stomach cancer.

[…]

“Proton pump inhibitors (PPIs) are an important treatment of Helicobacter pyloriinfection and have good safety records for short-term use,” says researcher Ian Wong from University College London.

“However, unnecessary long-term use should be avoided.”

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