The relevance seems to be that the kissing disease is more notable than once thought and thus perhaps should be targeted more in future treatments, along with the other associations found in the study.
A far-reaching study conducted by scientists at Cincinnati Children’s reports that the Epstein-Barr virus (EBV) — best known for causing mononucleosis — also increases the risks for some people of developing seven other major diseases.
Overall, the study sheds new light on how environmental factors, such as viral or bacterial infections, poor diet, pollution or other hazardous exposures, can interact with the human genetic blueprint and have disease-influencing consequences.
“Now, using genomic methods that were not available 10 years ago, it appears that components made by the virus interact with human DNA in the places where the genetic risk of disease is increased,” Harley says.
While the EBV-related findings involved more than 60 human proteins linked to seven diseases, the Cincinnati Children’s research team already has taken a huge next step. They applied the same analytic techniques to tease out connections between all 1,600 known transcription factors and the known gene variants associated with more than 200 diseases.
The results of that massive cross-analysis also appear in today’s study. Intriguing associations were documented involving 94 conditions.
“Our study has uncovered potential leads for many other diseases, including breast cancer,” Harley says. “We cannot possibly follow up on all of these, but we are hoping that other scientists will.”
In related news, scientists have also now confirmed a new DNA structure that’s inside human cells.